Fiona Lawson is returning home from a short vacation, and notices someone is moving into a house on her street. Or, is that her house? No, she'd know if someone had sold the house...wouldn't she?
BoJack Horseman is a dark comedy first, and a tragedy second. Going into the show with no knowledge other than a screencap, you can expect lots of laughs because—duh—it's about a cartoon horse that used to be the star of a beloved '90s sitcom called Horsin' Around. Half the characters are non-human animals, and half the jokes are based on that fact.
But BoJack is not a show to be underestimated, skipped, or ignored, whether it's the animated part that turns you off, or the anthropomorphic animal world that gives you the anti-furry willies. This show is too clever, too unexpected, too quippy, too brilliant to not suck in even the most resistant of viewers.